Registered Practical Nurse (RPN) Practice Test

A client experiences tolerance. What does this term refer to?

1. Resistance to treatment

2. Need for increased dosage to achieve desired effect

3. Successful detoxification

4. Ability to function without substances

The correct answer is: Need for increased dosage to achieve desired effect

The term "tolerance" in the context of pharmacology and substance use refers to a physiological phenomenon where a person's response to a drug decreases over time due to continued use. As a result, the individual requires a higher dosage of the substance to achieve the same therapeutic or euphoric effect that was previously experienced at a lower dose. This occurs because the body adapts to the presence of the drug, leading to reduced sensitivity. Understanding tolerance is crucial for healthcare professionals as it can impact treatment plans, medication management, and the assessment of a client's recovery progress. It is distinct from other concepts like resistance to treatment or detoxification, which relate to different aspects of substance use or medical management. Additionally, the ability to function without substances is indicative of recovery but does not specifically define tolerance.