Registered Practical Nurse (RPN) Practice Test

Addison's disease is known to potentially produce what psychiatric symptom?

1. Anxiety

2. Depression

3. Psychosis

4. Paranoia

The correct answer is: Psychosis

Addison's disease, which is characterized by insufficient production of hormones such as cortisol from the adrenal glands, can indeed lead to a variety of psychiatric symptoms, one of which can be psychosis. The underlying hormonal deficiency affects various bodily systems, including the central nervous system, potentially leading to mood disturbances and cognitive changes. Psychosis in individuals with Addison's disease may stem from the significant stress that the body experiences due to the hormone imbalance. This stress can overwhelm the individual, leading to symptoms such as hallucinations or delusions. Importantly, the hormonal changes associated with Addison's disease can alter neurotransmitter activity and contribute to the development of such severe psychiatric symptoms. On the other hand, while anxiety, depression, and paranoia can also be associated with Addison's disease due to stress and hormonal fluctuations, psychosis is a more severe manifestation that is less commonly observed, making it a notable concern in the management of patients with this condition. Recognizing the potential for psychosis in patients with Addison's disease emphasizes the importance of monitoring and addressing mental health symptoms in these individuals as part of comprehensive care.