Registered Practical Nurse (RPN) Practice Test

What is one of the earliest symptoms of Alzheimer's disease?

1. Difficulty with speech

2. Withdrawal from normal activities

3. Increased forgetfulness

4. Changes in mood

The correct answer is: Withdrawal from normal activities

In the context of Alzheimer's disease, increased forgetfulness is regarded as one of the most common and earliest symptoms. Individuals may begin to experience memory lapses, such as forgetting recently learned information, important dates, or repeatedly asking for the same information. This early cognitive decline primarily affects the ability to retain new information and recall past experiences, contributing to noticing that something is amiss. Other listed symptoms, while they can occur in the course of the disease, often become apparent as the condition progresses. Difficulty with speech may arise later as cognitive skills decline. Withdrawal from normal activities may happen as individuals become aware of their memory issues, but increased forgetfulness is typically more noticeable at the onset. Changes in mood can also be part of the disease's progression, but they often develop alongside memory issues rather than appearing first. Therefore, increased forgetfulness remains a key early indicator of Alzheimer's disease, prompting further evaluation and potential intervention.