Registered Practical Nurse (RPN) Practice Test

What may occur if a patient abruptly stops taking prescribed antipsychotic medication?

1. Improved stability

2. Withdrawal psychosis

3. Increased motivation

4. Heightened focus

The correct answer is: Withdrawal psychosis

When a patient abruptly stops taking prescribed antipsychotic medication, withdrawal psychosis can occur as a significant risk. Antipsychotic medications work to manage symptoms of mental health conditions such as schizophrenia and bipolar disorder by altering neurotransmitter activity in the brain, particularly dopamine. Discontinuing these medications suddenly can lead to a rebound effect, where symptoms may re-emerge or worsen, resulting in acute psychotic episodes. Patients may experience hallucinations, delusions, or severe agitation, which are hallmark symptoms of psychosis. This is particularly concerning for individuals whose conditions are sensitive to dosage changes or interruptions in treatment. The management of such conditions typically requires a gradual tapering of medication under medical supervision, rather than an abrupt cessation, to mitigate these risks and stabilize the patient’s mental health.