Registered Practical Nurse (RPN) Practice Test

When caring for a client on olanzapine (Zyprexa), which condition should the nurse assess for after 2 months of treatment?

1. Hypertension

2. Diabetes

3. Hyperlipidemia

4. Kidney dysfunction

The correct answer is: Diabetes

Olanzapine is an atypical antipsychotic medication commonly used to treat conditions such as schizophrenia and bipolar disorder. A key consideration with long-term use of olanzapine is its potential influence on metabolic parameters, including weight gain and changes in blood sugar levels. Assessing for diabetes after two months of treatment is particularly important because olanzapine has been associated with an increased risk of developing type 2 diabetes mellitus. This risk is compounded by the medication's tendency to cause significant weight gain, which is a known risk factor for insulin resistance and subsequently, diabetes. Monitoring clients for symptoms such as increased thirst, frequent urination, and unexplained weight loss is critical, as early detection can facilitate timely intervention and management of any emerging metabolic issues. This proactive assessment approach helps in mitigating the long-term risks associated with the medication. In contrast, the other options, although relevant to general health monitoring, are not as specifically linked to the known metabolic side effects of olanzapine over a two-month treatment period.