Registered Practical Nurse (RPN) Practice Test

When prescribing clozapine, what side effect should the nurse caution the client to report?

1. Severe headaches

2. Rapid weight gain

3. Excessive sweating

4. Nausea

The correct answer is: Rapid weight gain

When prescribing clozapine, it is important for the nurse to caution clients about the potential side effects associated with the medication. Rapid weight gain can be significant in this context because clozapine is known to cause metabolic changes, including increased appetite and alterations in glucose metabolism. Monitoring for weight gain is crucial, as it can lead to further health complications such as obesity, diabetes, and cardiovascular issues. Weight gain, especially when rapid, can indicate other underlying issues regarding the client’s metabolism or side effects that may need to be addressed. This might involve adjustments to the treatment plan or additional interventions to manage weight. Other side effects, such as severe headaches, excessive sweating, or nausea, while they may occur as well, do not typically have the same level of immediate concern or impact on long-term health management as rapid weight gain does in patients taking clozapine. Therefore, focusing on weight gain enables proactive management of the medication's side effects.