Registered Practical Nurse (RPN) Practice Test

Which of the following is an advantage of newer antidepressants?

1. They are less expensive

2. They have fewer side effects

3. They act more quickly

4. They require higher doses

The correct answer is: They have fewer side effects

Newer antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), are known for having fewer side effects compared to older classes of antidepressants like tricyclics and monoamine oxidase inhibitors (MAOIs). This reduced side effect profile is significant because it enhances patient compliance and overall quality of life. Common side effects of older antidepressants can include weight gain, sedation, and cardiovascular issues, which may deter patients from continuing their medication. In contrast, newer antidepressants typically have a more favorable side effect profile, which makes them safer and more tolerable for many patients. It's important for healthcare providers to understand these differences to better tailor treatment plans for individuals struggling with depression.