Registered Practical Nurse (RPN) Practice Test

Withdrawal effects are most commonly associated with which type of medications?

1. Beta-blockers and SSRIs

2. Antidepressants and antipsychotics

3. SSRIs and benzodiazepines

4. Narcotics and opioids

The correct answer is: SSRIs and benzodiazepines

Withdrawal effects are frequently associated with specific medications that can lead to physical or psychological dependence. In the case of SSRIs (Selective Serotonin Reuptake Inhibitors) and benzodiazepines, both categories of medications can cause withdrawal symptoms if they are discontinued suddenly or if their dosage is significantly reduced. SSRIs are commonly used to treat depression and anxiety disorders. When a patient stops taking an SSRI abruptly, they can experience withdrawal symptoms such as dizziness, nausea, irritability, and flu-like symptoms. This phenomenon occurs because the body needs time to adjust to the change in serotonin levels that result from stopping the medication. Benzodiazepines, on the other hand, are used to treat anxiety, insomnia, and seizure disorders. They are known for their calming effects, but they can also lead to physical dependence. Withdrawal from benzodiazepines can be more severe and may include symptoms such as increased anxiety, agitation, tremors, and, in extreme cases, seizures. This is due to the body's adaptation to the drug’s presence over time, making sudden cessation challenging. The association of withdrawal effects with SSRIs and benzodiazepines highlights the importance of careful management and gradual tapering of these medications to mitigate potential withdrawal symptoms.